Sterile composition

US10071061B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-10071061-B2
Application numberUS-201314400732-A
CountryUS
Kind codeB2
Filing dateMay 13, 2013
Priority dateMay 14, 2012
Publication dateSep 11, 2018
Grant dateSep 11, 2018

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

A sterile composition which comprises a protein and an aliphatic polyester containing the protein and is sterilized with radiation. In this sterile composition, the structure and function (activity) of the protein are retained.

First claim

Opening claim text (preview).

The invention claimed is: 1. A sterile composition sterilized with radiation comprising an aliphatic polyester and a protein selected from the group consisting of fibrinogen, enzymes, transport proteins, defense proteins, toxin proteins, protein hormones, growth factors and mixtures thereof, wherein at least part of the protein enters the inside of the aliphatic polyester as dispersion of particles of the protein or particles of a mixture of the protein and pharmaceutically acceptable additives, and wherein the sizes of the particles are not less than 0.01 μm. 2. The sterile composition according to claim 1 , wherein the aliphatic polyester is selected from the group consisting of polyglycolic acid, polylactic acid, polycaprolactone, copolymers thereof and mixtures thereof. 3. The sterile composition according to claim 1 which is in a fiber form. 4. The sterile composition according to claim 3 which is produced by an electro spinning method. 5. The sterile composition according to claim 1 which is in a film form. 6. The sterile composition according to claim 5 which is produced by a casting method.

Assignees

Inventors

Classifications

  • Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents · CPC title

  • acting on ester bonds (3.1), e.g. lipases, ribonucleases · CPC title

  • Thrombin (3.4.21.5) · CPC title

  • Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue (compositions for intravenous administration, normal injectable solutions or dispersions for, e.g. subcutaneous administration A61K9/0019; brain implants A61K9/0085; (coated) prostheses, catheters or stents A61L) · CPC title

  • Beta-glucosidase (3.2.1.21) · CPC title

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Frequently asked questions

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What does patent US10071061B2 cover?
A sterile composition which comprises a protein and an aliphatic polyester containing the protein and is sterilized with radiation. In this sterile composition, the structure and function (activity) of the protein are retained.
Who is the assignee on this patent?
Teijin Ltd, Teijin Pharma Ltd, The Chemo Sero Therapeutic Res Institute
What technology area does this patent fall under?
Primary CPC classification A61K9/70. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Sep 11 2018 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).