Compositions and methods for detecting, treating and preventing diseases and disorders

Patent metadata

Field	Value
Publication number	US-10066025-B2
Application number	US-201314414734-A
Country	US
Kind code	B2
Filing date	Jul 16, 2013
Priority date	Jul 16, 2012
Publication date	Sep 4, 2018
Grant date	Sep 4, 2018

Abstract

The invention described herein relates to the discovery that renalase, and fragments thereof, are useful for the treatment or prevention of cardiac and renal diseases or disorders. Thus, the invention relates to compositions comprising renalase, or fragments thereof, and methods for treating and preventing cardiac and renal disease or disorders.

First claim

The invention claimed is:

1. A composition comprising a polypeptide comprising at least one amino acid sequence selected from the group consisting of the amino acid sequence of SEQ ID NO: 2, and the amino acid sequence of SEQ ID NO: 4.

Assignees

• Univ Yale

Inventors

• Desir Gary

Classifications

• A61P9/12

  Antihypertensives · CPC title

• A61P9/00

  Drugs for disorders of the cardiovascular system · CPC title

• A61P35/00

  Antineoplastic agents · CPC title

• A61P9/10

  for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis · CPC title

• A61P43/00

  Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00 · CPC title