Method for measuring stable and reproducible electrode-tissue impedance

Patent metadata

Field	Value
Publication number	US-10065036-B2
Application number	US-90616707-A
Country	US
Kind code	B2
Filing date	Sep 28, 2007
Priority date	Sep 29, 2006
Publication date	Sep 4, 2018
Grant date	Sep 4, 2018

Abstract

The present invention is a method for measuring stable and reproducible electrode-tissue impedance, comprising preconditioning an electrode-tissue interface. Further aspect of the invention is a stimulation system for a visual prosthesis generating a stimulation signal to precondition the electrode-tissue interface, comprising a computer; software, loaded in the computer, adapted to perform a stimulating method for a visual prosthesis having a plurality of electrodes; a video processing unit; and an implanted neuron-stimulator.

First claim

What we claim is:

1. A stimulation system for a visual prosthesis generating a stimulation signal to precondition an electrode-tissue interface, comprising:
a computer;
an implanted neural-stimulator, including a plurality of electrodes suitable to contact neural tissue;

a video processing unit in communication with the computer and the implanted neural stimulator; and
software, loaded in the computer, adapted to instruct the implanted neural stimulator through the video processing unit to deliver a first small electrical charge causing a non-faradaic reaction in the electrode tissue interface, including charge balanced biphasic square wave current pulses, for a predetermined duration of 1 second to 10 minutes, to deliver a second electrical charge within a predetermined delay of the predetermined duration and measure impedance after delivering the second electrical charge, and then to perform a stimulating method for a visual prosthesis having a plurality of electrodes.

2. The stimulation system for a visual prosthesis according to claim 1 , configured to deliver the second electrical charge at similar electrode-tissue interface conditions to the first small electrical charge.

3. The stimulation system for a visual prosthesis according to claim 1 configured to deliver the first small electrical charge one electrode at a time or in groups of electrodes.

4. The stimulation system for a visual prosthesis according to claim 1 configured to deliver the first small electrical charge for all electrodes in an array of electrodes simultaneously.

5. The stimulation system for a visual prosthesis according to claim 4 configured to vary the first small electrical charge by pulse-width, amplitude and frequency.

6. The stimulation system for a visual prosthesis according to claim 1 , configured to deliver the first small electrical charge at 10-300 μA at 15-120 Hz with 0.1-2.0 ms pulse width.

7. The stimulation system for a visual prosthesis according to claim 1 , configured to deliver the first small electrical charge at 30-150 μA at 30-120 Hz with 0.2-1.0 ms pulse width.

8. The stimulation system for a visual prosthesis according to claim 1 , configured to deliver the first small electrical charge at 80-120 μA at 40-60Hz with 0.4-0.6 ms pulse width.

Assignees

• Hines Amy Chu Peishuan
• Zhou Dao Min
• Roy Arup
• Dai Rongqing
• Greenberg Robert J
• Second Sight Medical Products Inc

Inventors

• Hines Amy Chu Peishuan
• Zhou Dao Min
• Roy Arup
• Dai Rongqing
• Greenberg Robert J

Classifications

• A61N1/0543

  Retinal electrodes · CPC title

• A61N1/36046 Primary

  of the eye · CPC title