Biological fluid filters with port for optimized flow distribution

Patent metadata

Field	Value
Publication number	US-10064988-B2
Application number	US-201313923073-A
Country	US
Kind code	B2
Filing date	Jun 20, 2013
Priority date	Jun 20, 2013
Publication date	Sep 4, 2018
Grant date	Sep 4, 2018

Abstract

Devices for the removal of cells or other particles from a biological fluid are disclosed. The devices include a removal medium housed within a chamber of a housing. The devices include inlet and outlet ports carried by the walls. One or both of the ports includes a flow path portion having a chamber-communicating portion that has a cross-section that is larger than the cross-section of an adjacent flow path portion.

First claim

The invention claimed is:

1. A device for removing unwanted cells from a biological fluid comprising:
a) a housing comprising a pair of flexible walls defining an interior chamber between said walls, said housing having a top peripheral edge and a bottom peripheral edge;
b) a removal medium filter of non-woven fibers within said interior chamber;
c) an inlet port carried by one of said pair of housing walls and an outlet port carried by the other of said pair of housing walls, wherein said inlet port is closer to said top peripheral edge and said outlet port is closer to said bottom peripheral edge, said inlet port and said outlet port being located on said housing walls in diametrically opposed positions;
d) each of said ports defining a flow path, said flow path comprising a chamber-communicating portion at said housing wall and an adjacent portion wherein said chamber-communicating portion has a cross-section larger than the cross-section of said adjacent portion, wherein each of said inlet port and said outlet port comprises a flexible flared wall defining said chamber-communicating portion, wherein said flexible flared wall defining said chamber-communicating portion of said inlet port flares non-symmetrically outwardly relative to an axis that is generally perpendicular to said housing wall and wherein said flexible flared wall of said inlet port that is nearer said bottom peripheral edge flares outwardly from said adjacent portion at a greater angle relative to said axis than said flexible flared wall nearer said top peripheral edge, and wherein said chamber-communicating portion of said inlet port does not overlap with said chamber-communicating portion of said outlet port.

2. The device of claim 1 wherein said flexible flared wall of said outlet port defining said chamber-communicating portion flares outwardly relative to an axis that is generally perpendicular to said housing wall.

3. The device of claim 2 wherein said outlet port flexible flared wall defining said chamber-communicating portion of said outlet port flares outwardly symmetrically.

4. The device of claim 2 wherein said one of said outlet port flexible flared walls flares outwardly to a greater degree toward said top peripheral edge than toward said bottom peripheral edge.

5. The device of claim 1 wherein said ports are integrally molded with said housing walls.

6. The device of claim 1 wherein said ports are separately molded and separately attached to said housing walls.

7. The device of claim 1 wherein said removal medium filter comprises a plurality of layers of non-woven fibers.

8. The device of claim 1 wherein said removal medium filter comprises a porous filter for removing leukocytes from blood.

9. The device of claim 1 wherein said flexible walls are sealed together along their peripheries to provide an outer peripheral seal.

10. The device of claim 9 further comprising an inner seal spaced inwardly from said peripheral seal.

11. The device of claim 1 wherein said adjacent portion of said flow path is parallel to said housing.

12. The device of claim 1 wherein said flexible flared wall defining said chamber-communicating portion of said inlet port that is nearer said bottom peripheral edge flares outwardly between said adjacent portion and said housing wall at an angle of no greater than 89° relative to said axis.

13. The device of claim 12 wherein said flexible flared wall defining said chamber communicating portion of said inlet port that is nearer said bottom peripheral edge flares outwardly up to 60° relative to said axis.

14. The device of claim 1 wherein said chamber-communicating flow path portion has a diameter of about 0.25 to 2.0 cm.

15. The device of claim 1 wherein said inlet port flexible flared wall that is nearer said bottom peripheral edge includes only one flared wall portion between said adjacent portion and said housing wall.

16. The device of claim 15 wherein no part of said flared wall portion forms an angle greater than 89° relative to said axis.

Assignees

• Fenwal Inc

Inventors

• Calderon Carlos
• Lynn Daniel
• Verri Paolo

Classifications

• A61M1/0218

  with filters · CPC title

• A61M1/3635

  Constructional details · CPC title

• A61M1/3406

  Physical characteristics of the filtrate, e.g. urea · CPC title

• A61M2206/20

  having means for promoting or enhancing the flow, actively or passively · CPC title

• A61M1/3633 Primary

  Blood component filters, e.g. leukocyte filters · CPC title