Biological sterilization indicator

US10059977B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-10059977-B2
Application numberUS-201715484781-A
CountryUS
Kind codeB2
Filing dateApr 11, 2017
Priority dateMay 21, 2013
Publication dateAug 28, 2018
Grant dateAug 28, 2018

How to read this patent

A practical reading order for non-experts. Skip the full description unless you need deep technical detail.

  1. Title

    What the patent document calls the invention.

  2. Abstract

    A short plain-language summary of the technical disclosure.

  3. Assignees and inventors

    Who owns or filed the patent and who is credited as inventor.

  4. Key dates

    Filing, priority, publication, and grant dates set the timeline.

  5. First independent claim

    The legal scope of protection — read this for what is actually claimed.

  6. CPC / IPC classifications

    Technology tags used to group this patent with similar filings.

  7. Citations and related patents

    Prior art links and similar publications in this corpus.

Abstract

Official abstract text for this publication.

Spore carriers suitable for use in biological indicators are described. The spore carriers include a substrate such as polymeric film or non-woven web with a hydrophilic nanostructured layer bonded to it. Spores are bonded to the nanostructured layer. Nanostructured layers including nanoparticles, such as acid-sintered silica nanoparticles are described. Biological indicators including such spore carriers are also described.

First claim

Opening claim text (preview).

What is claimed is: 1. A biological sterilization indicator comprising: a housing defining a reservoir, the housing comprising a cap that includes one or more apertures to provide fluid communication between the reservoir and ambience; a frangible container within the housing; and a spore carrier comprising a substrate, a hydrophilic nanostructured layer bonded to a surface of the substrate and spores bonded to the nanostructured layer, wherein the nanostructured layer comprises silica nanoparticles. 2. The biological sterilization indicator of claim 1 , wherein the nanostructured layer has a receding contact angle of no greater than 50 degrees as measured by the Contact Angle Method. 3. The biological sterilization indicator of claim 1 , wherein the nanostructured layer has a receding contact angle of no greater than 20 degrees as measured by the Contact Angle Method. 4. The biological sterilization indicator of claim 1 , wherein the frangible container contains liquid. 5. The biological sterilization indicator of claim 4 , wherein the liquid comprises nutrient medium. 6. The biological sterilization indicator of claim 1 , wherein the silica nanoparticles are acid sintered. 7. The biological sterilization indicator of claim 1 , wherein the nanoparticles have an average diameter of no greater than 20 nm. 8. The biological sterilization indicator of claim 1 , wherein the nanostructured layer has an RMS roughness of at least 10 nm. 9. The biological sterilization indicator of claim 8 , the nanostructured layer has an RMS roughness of no greater than 500 nm. 10. The biological sterilization indicator of claim 1 , wherein the nanostructured layer further comprises microparticles. 11. The biological sterilization indicator of claim 1 , wherein the nanostructured layer further comprises a binder. 12. The biological sterilization indicator of claim 11 , wherein the binder comprises a tetraalkoxysilane. 13. The biological sterilization indicator of claim 1 , wherein the substrate is a polymeric substrate. 14. The biological sterilization indicator of claim 13 , wherein the polymeric substrate comprises polyester. 15. The biological sterilization indicator of claim 13 , wherein the polymeric substrate comprises polypropylene. 16. The biological sterilization indicator of claim 1 , wherein the substrate is a woven or non-woven web. 17. The biological sterilization indicator of claim 1 , wherein the substrate is a film. 18. The biological sterilization indicator of claim 1 , wherein the spores comprise at least one of Geobacillus stearothermophilus and Bacillus atrophaeus. 19. The biological sterilization indicator of claim 1 , wherein the spore carrier further comprises one or more wells. 20. The biological sterilization indicator of claim 1 , wherein the nanostructured layer comprises silica nanoparticles deposited out of an aqueous coating composition having a pH of less than 3.

Assignees

Inventors

Classifications

  • C12Q1/22Primary

    Testing for sterility conditions · CPC title

  • attached to the carrier via a bridging agent · CPC title

Patent family

Related publications grouped by family.

External sources

Frequently asked questions

Answers are generated from the same data shown on this page.

What does patent US10059977B2 cover?
Spore carriers suitable for use in biological indicators are described. The spore carriers include a substrate such as polymeric film or non-woven web with a hydrophilic nanostructured layer bonded to it. Spores are bonded to the nanostructured layer. Nanostructured layers including nanoparticles, such as acid-sintered silica nanoparticles are described. Biological indicators including such spo…
Who is the assignee on this patent?
3M Innovative Properties Co
What technology area does this patent fall under?
Primary CPC classification C12Q1/22. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Aug 28 2018 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 3 related publications on this page (citations in our corpus or others sharing the same primary CPC).