Sample analysis method
US-2015219593-A1 · Aug 6, 2015 · US
US10058821B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10058821-B2 |
| Application number | US-201314025905-A |
| Country | US |
| Kind code | B2 |
| Filing date | Sep 13, 2013 |
| Priority date | Sep 13, 2013 |
| Publication date | Aug 28, 2018 |
| Grant date | Aug 28, 2018 |
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A membrane structure is provided. The membrane structure may include: a membrane; at least one hole extending into the membrane configured to receive a fluid. The membrane may include a plurality of electrodes arranged to provide one or more electric fields to control a movement of the fluid within the at least one hole.
Opening claim text (preview).
What is claimed is: 1. A membrane structure, comprising: a membrane; at least one hole extending through the membrane, the at least one hole configured to receive a fluid; the membrane comprising an isolating material and a plurality of electrodes arranged sequentially along a longitudinal axis of the at least one hole to provide one or more electric fields to control a movement of the fluid within the at least one hole, wherein the isolating material insulates the plurality of electrodes at least from the at least one hole; and a plurality of terminals, each terminal being electrically conductively coupled to a respective electrode of the plurality of electrodes, each terminal configured to receive an individual electrical potential; wherein the plurality of electrodes comprises: opening electrodes at either opening of the at least one hole and at least one central electrode arranged between the opening electrodes, wherein the at least one central electrode has a thickness greater than a thickness of the opening electrodes. 2. The membrane structure of claim 1 , wherein the fluid comprises a liquid. 3. The membrane structure of claim 1 , wherein the membrane comprises a first side and a second side opposite the first side; wherein the membrane structure further comprises a first container coupled to the first side of the membrane, the first container configured to receive the fluid and to supply the fluid to the at least one hole. 4. The membrane structure of claim 3 , further comprising: a first electrode arranged in the first container. 5. The membrane structure of claim 1 , wherein the membrane comprises a first side and a second side opposite the first side; wherein the membrane structure further comprises a second container coupled to the second side of the membrane, the second container configured to receive at least one of the fluid via the at least one hole and a further fluid. 6. The membrane structure of claim 5 , further comprising: a second electrode arranged in the second container. 7. The membrane structure of claim 1 , wherein the at least one hole comprises a plurality of holes. 8. The membrane structure of claim 1 , wherein the at least one hole comprises at least one of a micropore and a nanopore. 9. A membrane structure, comprising: a membrane having a first side and a second side opposite the first side; at least one receptacle extending into the membrane from the first side without extending through to the second side, the at least one receptacle configured to receive a fluid; and the membrane comprising a plurality of electrodes arranged sequentially along a depth of the at least one receptacle to provide one or more electric fields to control a movement of the fluid within the at least one receptacle. 10. The membrane structure of claim 9 , further comprising: one or more sensing electrodes in the at least one receptacle, the sensing electrode configured to detect a selection from the group consisting of one or more materials, one or more molecules, one or more ions, and any combination thereof. 11. The membrane structure of claim 10 , further comprising: one or more transistors in the at least one receptacle, the one or more transistors configured to detect a selection from the group consisting of one or more materials, one or more molecules, one or more ions, and any combination thereof. 12. A membrane structure, comprising: a membrane; at least one hole extending through the membrane, the at least one hole configured to receive a fluid; the membrane comprising an isolating material and a plurality of electrodes arranged sequentially along a longitudinal axis of the at least one hole to provide one or more electric fields to control a movement of the fluid within the at least one hole, wherein the isolating material insulates the plurality of electrodes at least from the at least one hole; and a plurality of terminals, each terminal being electrically conductively coupled to a respective electrode of the plurality of electrodes, each terminal configured to receive an individual electrical potential; wherein the at least one hole further comprises a porous material at least partially in the at least one hole. 13. The membrane structure of claim 1 , wherein the at least one hole further comprises a reactive material configured to react with the fluid. 14. The membrane structure of claim 4 , wherein the first electrode is formed from a first material and the plurality of electrodes are formed from a second material, wherein the first material is different from the second material. 15. A membrane structure, comprising: a membrane; at least one hole extending through the membrane, the at least one hole configured to receive a fluid and wherein the at least one hole comprises at least one of a micropore and a nanopore; and the membrane comprising an isolating material and a plurality of electrodes arranged sequentially along a longitudinal axis of the at least one hole to provide one or more electric fields to control a movement of the fluid within the at least one hole, wherein each of the plurality of electrodes is configured to receive an individual electrical potential and wherein the isolating material insulates the plurality of electrodes at least from the at least one hole; wherein the plurality of electrodes comprises: opening electrodes at either opening of the at least one hole and at least one central electrode arranged between the opening electrodes, wherein the at least one central electrode has a thickness greater than a thickness of the opening electrodes. 16. The membrane structure of claim 15 , wherein the membrane comprises a first side and a second side opposite the first side; wherein the membrane structure further comprises a first container coupled to the first side of the membrane, the first container configured to receive the fluid and to supply the fluid to the at least one hole; and a first electrode arranged in the first container. 17. The membrane structure of claim 16 , wherein the membrane structure further comprises a second container coupled to the second side of the membrane, the second container configured to receive at least one of the fluid via the at least one hole and a further fluid; and a second electrode arranged in the second container. 18. The membrane structure of claim 12 , wherein within the porous material is a reactive material.
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