Film composition for hard capsule shells
US-2015150817-A1 · Jun 4, 2015 · US
US10058617B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10058617-B2 |
| Application number | US-201615376921-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 13, 2016 |
| Priority date | Dec 16, 2015 |
| Publication date | Aug 28, 2018 |
| Grant date | Aug 28, 2018 |
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Provided is a composition for forming a film, the composition not having completely dissolved hydroxypropyl methyl cellulose (HPMC), and enabling formation of the film having a uniform thickness by suppressing the viscosity increase of the composition around an immersion temperature of 50° C. More specifically provided is a composition for forming a film, the composition comprising hypromellose having methoxy group content of 28.0 to 30.0% by weight and hydroxypropoxy group content of 7.6 to 8.5% by weight, wherein a 2% by weight aqueous solution of the hypromellose provides a viscosity at 20° C. of 4.0 to 6.5 mPa·s, a 20% by weight dispersion of the hypromellose provides a viscosity at 50° C. of 2,000 to 11,000 mPa·s, and a 20% by weight aqueous solution of the hypromellose provides a gelation temperature of 54 to 57° C.; and a solvent.
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The invention claimed is: 1. A composition for forming a film, the composition comprising: hypromellose having methoxy group content of 28.0 to 30.0% by weight and hydroxypropoxy group content of 7.6 to 8.5% by weight, wherein a 2% by weight aqueous solution of the hypromellose provides a viscosity at 20° C. of 4.0 to 6.5 mPa·s, a 20% by weight dispersion of the hypromellose provides a viscosity at 50° C. of 2,000 to 11,000 mPa·s, and a 20% by weight aqueous solution of the hypromellose provides a gelation temperature of 54 to 57° C.; and a solvent. 2. The composition according to claim 1 , further comprising a gelling agent. 3. The composition according to claim 1 , further comprising a gelling adjuvant. 4. The composition according to claim 2 , further comprising a gelling adjuvant.
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