Method of treatment of aggression

US10058556B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-10058556-B2
Application numberUS-201715782334-A
CountryUS
Kind codeB2
Filing dateOct 12, 2017
Priority dateDec 19, 2008
Publication dateAug 28, 2018
Grant dateAug 28, 2018

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

The invention comprises a method of treatment of aggression and similar behavioral syndromes, such as impulsivity and irritability, by a pharmaceutical agent exhibiting combined D2 and D5 antagonistic activity.

First claim

Opening claim text (preview).

What is claimed is: 1. A method of treating impulsive aggression in an attention deficit hyperactivity disorder (ADHD) patient, comprising: administering 10 mg/day to 200 mg/day of molindone to a patient with ADHD as the sole condition and manifesting impulsive aggression not controlled by ADHD treatment. 2. The method of claim 1 , wherein 15 to 120 mg/day of molindone is administered. 3. The method of claim 1 , wherein the administration decreases side effects associated with molindone. 4. The method of claim 3 , wherein the side effects are selected from drowsiness, depression, hyperactivity, euphoria, extrapyramidal reactions, akathisia, akinesia, dystonic syndrome, tardive dyskinesia, tachycardia, nausea, dry mouth, urinary retention, and constipation. 5. The method of claim 1 , wherein the administration results in reduction of undesirable behavior and intolerable side effects. 6. The method of claim 1 , wherein the patient is a child.

Assignees

Inventors

Classifications

  • Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00 · CPC title

  • Hypnotics; Sedatives · CPC title

  • Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia · CPC title

  • Drugs for disorders of the nervous system · CPC title

  • not condensed and containing further heterocyclic rings, e.g. timolol · CPC title

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Frequently asked questions

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What does patent US10058556B2 cover?
The invention comprises a method of treatment of aggression and similar behavioral syndromes, such as impulsivity and irritability, by a pharmaceutical agent exhibiting combined D2 and D5 antagonistic activity.
Who is the assignee on this patent?
Supernus Pharmaceuticals Inc
What technology area does this patent fall under?
Primary CPC classification A61K31/5377. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Aug 28 2018 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 1 related publication on this page (citations in our corpus or others sharing the same primary CPC).