Sample container cap with centrifugation status indicator device

Patent metadata

Field	Value
Publication number	US-10048284-B2
Application number	US-201514699734-A
Country	US
Kind code	B2
Filing date	Apr 29, 2015
Priority date	Nov 7, 2011
Publication date	Aug 14, 2018
Grant date	Aug 14, 2018

Abstract

A sample container cap is disclosed. The sample cap container includes a sample cap body capable of covering an opening of a sample container and a centrifugation status indicator device in the top of the sample cap body. The centrifugation status indicator device includes: a first substance having a first density and a first color, and a second substance having a second density and a second color. The centrifugation status indicator device displays the first substance when the sample container has been centrifuged. The first substance can be a gel, and the second substance can include a plurality of particles. The second density is higher than the first density and the second color is different from the first color.

First claim

What is claimed is:

1. A sample container cap comprising:
a sample cap body capable of covering an opening of a sample container; and
a centrifugation status indicator device in the top of the sample cap body, wherein the centrifugation status indicator device comprises:
a first substance having a first density and a first color, wherein the first substance comprises a gel; and
a second substance having a second density and a second color, wherein the second substance comprises a plurality of particles, wherein the second density is higher than the first density and wherein the second color is different from the first color, and wherein the centrifugation status indicator device displays the first substance when the sample container has been centrifuged.

2. The sample container cap of claim 1 , wherein the first and second substances are combined after centrifugation but are not combined without centrifugation.

3. The sample container cap of claim 1 wherein the centrifugation status indicator device comprises a combination of materials that change appearance according to applied centrifugation force and time.

4. The sample container cap of claim 1 wherein the sample cap body is transparent.

5. The sample container cap of claim 4 wherein the sample cap body is cylindrical.

6. The sample container cap of claim 4 wherein the sample cap body comprises a cap thread portion.

7. The sample container cap of claim 1 wherein the sample cap body includes a cylindrical cap thread portion and a cylindrical cap top portion, separated by a circular portion.

8. A sample container cap comprising:
a sample cap body capable of covering an opening of a sample container; and
a centrifugation status indicator device in the top of the sample cap body, wherein the centrifugation status indicator device comprises a pressure sensitive device extending in a first direction and transparent cylindrical elements that contact the pressure sensitive device and that extend perpendicular to the first direction of the pressure sensitive device, wherein the transparent cylindrical elements are configured to press onto the pressure sensitive device during centrifugation.

9. The sample container cap of claim 8 wherein the pressure sensitive device comprises a foil configured to change appearance in response to applied pressure.

10. The sample container cap of claim 9 wherein the foil is configured to change color in response to applied pressure.

11. The sample container cap of claim 8 wherein the pressure sensitive device comprises a pressure sensitive foil.

12. A method comprising:
attaching a sample container cap comprising a sample cap body, and a centrifugation status indicator device in the top of the sample cap body, to a sample container body containing a sample; and
centrifuging the sample in the sample container body, wherein the centrifugation status indicator indicates a status of centrifugation, wherein the centrifugation status indicator device comprises:
a first substance having a first density and a first color, wherein the first substance comprises a gel; and
a second substance having a second density and a second color, wherein the second substance comprises a plurality of particles, wherein the second density is higher than the first density and wherein the second color is different from the first color, and wherein the centrifugation status indicator device displays the first substance when the sample container has been centrifuged.

13. The method of claim 12 , wherein the centrifugation status indicator device comprises a combination of materials that change appearance according to applied centrifugation force and time.

14. The method of claim 12 , wherein the sample cap body is transparent.

15. The method of claim 12 , wherein the sample cap body comprises a cap thread portion.

16. A method comprising:
attaching a sample container cap comprising a sample cap body, and a centrifugation status indicator device in the top of the sample cap body, to a sample container body containing a sample; and
centrifuging the sample in the sample container body, wherein the centrifugation status indicator indicates a status of centrifugation, wherein the centrifugation status indicator device comprises a pressure sensitive device and transparent cylindrical elements that are perpendicular to the pressure sensitive device and contact the pressure sensitive device, wherein the transparent cylindrical elements press onto the pressure sensitive device during centrifuging the sample.

17. The method of claim 16 wherein the pressure sensitive device comprises a foil configured to change appearance in response to applied pressure.

Assignees

• Beckman Coulter Inc

Inventors

• Müller Martin
• Weihs Andreas
• Gunzer Gerhard
• Eberhardt Michael

Classifications

• G01F23/292

  Light {, e.g. infrared or ultraviolet} · CPC title

• B65D2203/12

  Audible, olfactory or visual signalling means (B65D51/248, B65D55/028, B65D79/02 and B65D81/24 take precedence) · CPC title

• B65D51/24

  combined {or co-operating} with auxiliary devices for non-closing purposes · CPC title

• B65D25/108

  Devices, e.g. plates, presenting apertures through which the articles project · CPC title

• B01L2400/0487

  fluid pressure, pneumatics · CPC title