Substituted aminopurine compounds, compositions thereof, and methods of treatment therewith
US-2017042902-A1 · Feb 16, 2017 · US
Solid forms of (1S,4S)-4-(2-(((3S,4R)-3-fluorotetrahydro-2H-pyran-4-yl)amino)-8-((2,4,6-trichlorophenyl)amino)-9H-purin-9-yl)-1-methylcyclohexane-1-carboxamide and methods of their use
US10047090B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10047090-B2 |
| Application number | US-201715475836-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 31, 2017 |
| Priority date | Apr 1, 2016 |
| Publication date | Aug 14, 2018 |
| Grant date | Aug 14, 2018 |
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Abstract
Official abstract text for this publication.
Provided herein are formulations, solid forms and methods of use relating to (1s,4s)-4-(2-(((3S,4R)-3-fluorotetrahydro-2H-pyran-4-yl)amino)-8-((2,4,6-trichlorophenyl)amino)-9H-purin-9-yl)-1-methylcyclohexane-1-carboxamide.
First claim
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What is claimed is: 1. A crystal form comprising Compound 1, or a tautomer thereof: which has an X-ray powder diffraction pattern comprising peaks at 7.3, 8.5, 18.2, and 21.3° 2θ (±0.2° 2θ). 2. A crystal form comprising a citrate salt of Compound 1, or a tautomer thereof: which has an X-ray powder diffraction pattern comprising peaks at 4.8, 9.6, 18.9, and 19.2° 2θ (±0.2° 2θ). 3. A crystal form comprising a hydrochloride salt of Compound 1, or a tautomer thereof: which has an X-ray powder diffraction pattern comprising peaks at 9.0, 9.8, 9.9, and 16.7° 2θ (±0.2° 2θ). 4. A pharmaceutical composition comprising said solid form of claim 1 , and a pharmaceutical carrier.
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Frequently asked questions
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- What does patent US10047090B2 cover?
- Provided herein are formulations, solid forms and methods of use relating to (1s,4s)-4-(2-(((3S,4R)-3-fluorotetrahydro-2H-pyran-4-yl)amino)-8-((2,4,6-trichlorophenyl)amino)-9H-purin-9-yl)-1-methylcyclohexane-1-carboxamide.
- Who is the assignee on this patent?
- Signal Pharm Llc
- What technology area does this patent fall under?
- Primary CPC classification C07D473/32. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Aug 14 2018 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 5 related publications on this page (citations in our corpus or others sharing the same primary CPC).