Useful active agent for preventing and/or treating dandruff conditions of the scalp

Patent metadata

Field	Value
Publication number	US-10046014-B2
Application number	US-201214110049-A
Country	US
Kind code	B2
Filing date	Apr 5, 2012
Priority date	Apr 5, 2011
Publication date	Aug 14, 2018
Grant date	Aug 14, 2018

Abstract

The present invention relates to the cosmetic use of a lysate of a bacterium or bacteria belonging to the Vitreoscilla sp. genus (in particular the species: Vitreoscilla filiformis) in a complete fermentation medium, as an active agent for preventing and/or treating dandruff conditions of the scalp, including dandruff conditions of the scalp associated with a prevalence of pathogenic microorganisms on the scalp and/or an imbalance of the scalp ecoflora.

First claim

The invention claimed is:

1. A process for preventing, treating, or both preventing and treating dandruff condition of an individual, the process comprising:
administering to an individual in need thereof, one lysate of a bacterium, said lysate consisting of a lysate of a bacterium belonging to the genus of Vitreoscilla , and being administered with all or parts, in terms of amount, of a complete fermentation medium, said complete fermentation medium resulting from the culturing process having been used for the growth and the cell lysis of said bacterium, said medium having undergone no additional manipulation aimed at separating and/or removing all or part of its non-aqueous constituents,
wherein said lysate with complete fermentation medium comprises:
cytoplasmic fractions,
cell wall fragments,
metabolites formed, released, or both formed and released during cell lysis of said bacterium, and
water-soluble metabolites generated and released spontaneously by said bacterium in the fermentation medium.

2. The process of claim 1 , wherein the bacterium is Vitreoscilla filiformis strain.

3. The process of claim 1 , wherein the bacterium is Vitreoscilla filiformis (ATCC 15551) strain.

4. The process of claim 1 , wherein the process is carried out topically.

5. The process of claim 1 , wherein the dandruff condition is associated with at least one condition of a proliferation of pathogenic microorganisms on a scalp and an imbalance of scalp ecoflora in the individual.

6. The process of claim 1 , wherein the genus of Vitreoscilla is Vitreoscilla filiformis.

7. The process of claim 1 , wherein said complete fermentation medium is taken directly from the culturing process and has not undergone any additional manipulation aimed at separating and/or removing other than sterilization of its non-aqueous constituents.

8. The process of claim 7 , wherein the bacterium is Vitreoscilla filiformis strain.

Assignees

• Hilaire Pascal
• Mahe Yann
• Martin Richard
• Oreal

Inventors

• Hilaire Pascal
• Mahe Yann
• Martin Richard

Classifications

• A61K2800/85

  Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine · CPC title

• A61K2800/74

  Biological properties of particular ingredients · CPC title

• A61Q5/006 Primary

  Antidandruff preparations · CPC title

• A61K8/99 Primary

  from microorganisms other than algae or fungi, e.g. protozoa or bacteria · CPC title

• A61K35/74 Primary

  Bacteria (therapeutic use of a bacterial protein A61K38/00) · CPC title