Transfer hydrogenation of cyclopamine analogs
US-2017029433-A1 · Feb 2, 2017 · US
Methods of use of cyclopamine analogs
US10045970B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10045970-B2 |
| Application number | US-201715585038-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 2, 2017 |
| Priority date | Dec 28, 2006 |
| Publication date | Aug 14, 2018 |
| Grant date | Aug 14, 2018 |
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- Title
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- Abstract
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Abstract
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The invention provides methods for treating various conditions using derivatives of cyclopamine having the following formula:
First claim
Opening claim text (preview).
It is claimed: 1. A method for treating basal cell carcinoma in a subject, the method comprising administering to the subject a composition comprising a compound having the structure: or a pharmaceutically acceptable acid salt thereof, and a pharmaceutically acceptable carrier or diluent. 2. The method of claim 1 , wherein the compound is in the form of a pharmaceutically acceptable acid salt. 3. The method of claim 2 , wherein the salt is an inorganic acid salt. 4. The method of claim 2 , wherein the salt is a hydrochloric acid salt. 5. The method of claim 1 , wherein the composition is a liquid composition. 6. The method of claim 1 , wherein the composition is in the form of a cream, ointment, or spray. 7. The method of claim 1 , wherein the composition is administered topically. 8. The method of claim 1 , wherein said administering is carried out in combination with an additional cancer treatment. 9. The method of claim 8 , wherein said additional cancer treatment comprises radiation, surgery, or administration of a second chemotherapeutic agent.
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Classifications
Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00 · CPC title
specific for metastasis · CPC title
specific for leukemia · CPC title
Antineoplastic agents · CPC title
attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin {(digitoxin A61K31/7048)} · CPC title
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Frequently asked questions
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- What does patent US10045970B2 cover?
- The invention provides methods for treating various conditions using derivatives of cyclopamine having the following formula:
- Who is the assignee on this patent?
- Infinity Pharmaceuticals Inc
- What technology area does this patent fall under?
- Primary CPC classification C07D491/10. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Aug 14 2018 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 10 related publications on this page (citations in our corpus or others sharing the same primary CPC).