Methods, compositions, and delivery systems for therapeutic skin treatments
US-2024390236-A1 · Nov 28, 2024 · US
US10045927B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10045927-B2 |
| Application number | US-201415107562-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 10, 2014 |
| Priority date | Dec 23, 2013 |
| Publication date | Aug 14, 2018 |
| Grant date | Aug 14, 2018 |
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Surface staining can be minimized or eliminated by providing an oral care composition comprising a first film comprising a pigment; and optionally a second film; wherein the first film has a dissolution rate in aqueous media that is inversely proportional to its thickness, wherein the first film is in the form of a particle.
Opening claim text (preview).
What is claimed is: 1. A toothpaste composition comprising a single-layer film comprising, by dry weight of the film, 20-60 wt. % cellulose ether selected from alkylcellulose, hydroxyalkyl cellulose, and combinations thereof; 10-30 wt. % plasticizer selected from sorbitol, propylene glycol, glycerol, and polyethylene glycol; 1-5 wt. % non-ionic polysorbate surfactant; and 15-55 wt. % pigment; wherein the film is dissolved after a period of greater than 30 seconds and less than 180 seconds of brushing, scrubbing or agitation in the oral cavity in the presence of water; and the film is in the form of a particle having a size of 30 to 50 mesh. 2. The composition of claim 1 wherein the cellulose ether comprises a hydroxylalkyl cellulose. 3. The composition according to claim 1 , wherein the cellulose ether comprises an alkylcellulose which comprises methylcellulose. 4. The composition according to claim 2 , wherein the hydroxyalkyl cellulose is selected from: hydroxypropyl methyl cellulose, hydroxyethylpropyl cellulose, hydroxybutyl methyl cellulose, carboxymethyl cellulose and a combination of two or more thereof. 5. The composition according to claim 1 , wherein the plasticizer comprises propylene glycol. 6. The composition according to claim 1 , wherein the non-ionic polysorbate surfactant comprises polysorbate 80. 7. The composition according to claim 1 , wherein the pigment comprises Pigment Blue 15 [147-14-8], Pigment Blue 15:2, Pigment Green 7 [1328-53-6], Pigment Orange 5 [3468-63-1], Pigment Red 4 [2814-77-9], Pigment Red 5 [6410-41-9], Pigment Red 48:4 [5280-66-0], Pigment Red 53:1 [5160-02-1], Pigment Red 57 [5858-81-1], Pigment Red 57:1 [5281-04-9]; Pigment Red 57:2 Barium Lake [17852-98-1], Pigment Red 63:1 [6417-83-0], Pigment Red 64:1 [6371-76-2], Pigment Red 68 [5850-80-6], Pigment Red 83, Pigment Red 90:1 Aluminum Lake [16508-80-8], Pigment Red 112 [6535-46-2], Pigment Red 172 Aluminum Lake [12227-78-0], Pigment Red 173 Aluminum Lake, Pigment Violet 19 [1047-16-1], Pigment Yellow 1 [2512-29-0], Pigment Yellow 3 [6486-23-3], Pigment Yellow 12 [6358-85-6], Pigment Yellow 13 [5102-83-0], Pigment Yellow 73 [13515-40-7] or a combination of any of these pigments. 8. The composition according to claim 1 , wherein the film comprises, by dry weight of the film, 20-60 wt. % of a cellulose ether selected from methyl cellulose, hydroxypropylmethyl cellulose, and a combination thereof; 10-30 wt. % propylene glycol; 1-5 wt. % polysorbate 80; and 15-55 wt. % pigment. 9. The oral care composition of claim 1 , wherein the composition further comprises an active agent selected from the group consisting of flavoring, an anesthetic, an antibacterial agent, an amino acid, a fluoride source, a whitening agent, a zinc compound and mixtures thereof. 10. The oral care composition of claim 1 , wherein the oral care composition further comprises an anionic surfactant in an amount from 1.5 wt. % to 5.0 wt. %. 11. The oral care composition of claim 1 , wherein the oral care composition further comprises an anionic surfactant in an amount from 1.5 wt. % to 2.0 wt. % and wherein the anionic surfactant is sodium lauryl sulfate.
Platelets; Flakes · CPC title
containing sulfuric acid derivatives, e.g. sodium lauryl sulfate · CPC title
containing more than one hydroxy group · CPC title
Cellulose; Quaternized cellulose derivatives · CPC title
Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses · CPC title
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