Method for stirring a mixed liquid in an automatic analyzer including first and second stirring mechanisms

Patent metadata

Field	Value
Publication number	US-10041964-B2
Application number	US-201615083809-A
Country	US
Kind code	B2
Filing date	Mar 29, 2016
Priority date	May 8, 2008
Publication date	Aug 7, 2018
Grant date	Aug 7, 2018

Abstract

In the field of automatic analyzers, as items to be analyzed are increase, various reagents differing in such properties as liquid viscosity and contact angle are being used more frequently, and this trend is expected to continue. Also, reagents now take various forms (e.g., a concentrated reagent to be diluted by the water of an automatic analyzer), and so does dilution water. Such being the case, the invention provides an automatic analyzer capable of sufficient stirring regardless of items to be analyzed. To sufficiently stir a substance to which a reagent has been added, the automatic analyzer is designed to alter stirring conditions after a given amount of time has passed since the addition of that reagent.

First claim

What is claimed is:

1. A method for stirring a mixed fluid liquid consisting of a sample and a reagent in an automatic analyzer including a reaction vessel to which the sample and the reagent are injected, a reaction disk for holding the reaction vessel, a first stirring mechanism and a second stirring mechanism for stirring the mixed liquid consisting of the sample and the reagent in the reaction vessel, and a control unit for controlling operations of the reaction disk and the first stirring mechanism and the second stirring mechanism, the method comprising the steps of:
storing a first stirring condition and a second stirring condition in a storing unit, wherein the first stirring condition and the second stirring condition are each set according to a viscosity of the mixed liquid;
stirring the mixed liquid consisting of the sample and the reagent by the first stirring mechanism applying only the first stirring condition stored in the storing unit, and thereafter, moving the reaction vessel with the mixed liquid by rotating the reaction disk holding the reaction vessel; and
stirring the mixed liquid consisting of the sample and the reagent by the second stirring mechanism applying only the second stirring condition stored in the storing unit,
wherein the first stirring condition is different from the second stirring condition.

2. The method according to claim 1 , wherein the automatic analyzer further includes a photometric instrument, and the method further comprises the step of:
measuring a mixed liquid which has been stirred by applying the first stirring condition and the second stirring condition.

3. The method according to claim 2 , wherein the first stirring mechanism and the second stirring mechanism are respectively comprised of a plurality of piezoelectric elements having a plurality of electrodes as sound sources, and the control unit controls the application of the first stirring condition and the second stirring condition in such a manner that electrodes of the first stirring mechanism selected by applying the first stirring condition are different from electrodes of the second stirring mechanism selected by applying the second stirring condition.

4. The method according to claim 1 , wherein the first stirring mechanism and the second stirring mechanism are respectively comprised of a plurality of piezoelectric elements having a plurality of electrodes as sound sources, and the control unit controls the application of the first stirring condition and the second stirring condition in such a manner that electrodes of the first stirring mechanism selected by applying the first stirring condition are different from electrodes of the second stirring mechanism selected by applying the second stirring condition.

5. A method for stirring a mixed liquid consisting of a sample, a first reagent, and a second reagent in an automatic analyzer including a reaction vessel to which the sample, the first reagent and the second reagent are injected, a reaction disk for holding the reaction vessel, a first stirring mechanism and a second stirring mechanism for stirring the mixed liquid consisting of the sample, the first reagent and the second reagent in the reaction vessel, and a control unit for controlling operations of the reaction disk and the first stirring mechanism and the second stirring mechanism, the method comprising the steps of:
storing a first stirring condition and a second stirring condition in a storing unit, wherein the first stirring condition and the second stirring condition are each set according to a viscosity of the mixed liquid;
stirring the mixed liquid consisting of the sample, the first reagent and the second reagent by the first stirring mechanism applying only the first stirring condition stored in the storing unit, and thereafter, moving the reaction vessel with the mixed liquid by rotating the reaction disk holding the reaction vessel; and
stirring the mixed liquid consisting of the sample, the first reagent and the second reagent by the second stirring mechanism applying only the second stirring condition stored in the storing unit,
wherein the first stirring condition is different from the second stirring condition.

6. The method according to claim 5 , wherein the automatic analyzer further includes a photometric instrument, and the method further comprises the step of:
measuring a mixed liquid which has been stirred by applying the first stirring condition and the second stirring condition.

7. The method according to claim 6 , wherein the first stirring mechanism and the second stirring mechanism are respectively comprised of a plurality of piezoelectric elements having a plurality of electrodes as sound sources, and the control unit controls the application of the first stirring condition and the second stirring condition in such a manner that electrodes of the first stirring mechanism selected by applying the first stirring condition are different from electrodes of the second stirring mechanism selected by applying the second stirring condition.

8. The method according to claim 5 , wherein the first stirring mechanism and the second stirring mechanism are respectively comprised of a plurality of piezoelectric elements having a plurality of electrodes as sound sources, and the control unit controls the application of the first stirring condition and the second stirring condition in such a manner that electrodes of the first stirring mechanism selected by applying the first stirring condition are different from electrodes of the second stirring mechanism selected by applying the second stirring condition.

Assignees

• Hitachi High Tech Corp

Inventors

• Yabutani Chie
• Matsubara Shigeki

Classifications

• G01N1/38

  Diluting, dispersing or mixing samples · CPC title

• G01N35/0092 Primary

  Scheduling · CPC title

• Y10T436/25

  including sample preparation · CPC title

• G01N2035/00554

  using ultrasound · CPC title

• G01N2035/00514

  Stationary mixing elements · CPC title