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Functionally switchable self-assembled coating compound for controlling translocation of molecule through nanopores
US10040682B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10040682-B2 |
| Application number | US-201213465280-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 7, 2012 |
| Priority date | Apr 4, 2012 |
| Publication date | Aug 7, 2018 |
| Grant date | Aug 7, 2018 |
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Abstract
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A technique for a nanodevice is provided. The nanodevice includes a fluidic cell, and a membrane dividing the fluidic cell. A nanopore is formed through the membrane, and the nanopore is coated with an organic compound. A first part of the organic compound binds to a surface of the nanopore and a second part of the organic compound is exposed freely inside of the nanopore. The second part of the organic compound is configured to be switched among a first neutral hydrophilic end group, a second negatively charged hydrophilic end group, and a third neutral hydrophobic end group based on a switching mechanism.
First claim
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What is claimed is: 1. A method for functionally switching an organic compound in a nanopore, the method comprising: coating the nanopore in a nanodevice with the organic compound, the nanodevice comprising a fluidic cell, a membrane dividing the fluidic cell, and the nanopore formed through the membrane such that the membrane exposed in the nanopore is coated with the organic compound selected from a group comprising 4-carboxylbenzyl phosphonic acid and 4-aminophenylhydroxamic ac…
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- What does patent US10040682B2 cover?
- A technique for a nanodevice is provided. The nanodevice includes a fluidic cell, and a membrane dividing the fluidic cell. A nanopore is formed through the membrane, and the nanopore is coated with an organic compound. A first part of the organic compound binds to a surface of the nanopore and a second part of the organic compound is exposed freely inside of the nanopore. The second part of th…
- Who is the assignee on this patent?
- Afzali Ardakani Ali, Harrer Stefan, Luan Binquan, and 4 more
- What technology area does this patent fall under?
- Primary CPC classification G01N27/00. Mapped technology areas include Physics.
- When was this patent published?
- Publication date Tue Aug 07 2018 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 7 related publications on this page (citations in our corpus or others sharing the same primary CPC).