Implantable prosthesis having acellular tissue attachments

Patent metadata

Field	Value
Publication number	US-10039633-B2
Application number	US-201314406263-A
Country	US
Kind code	B2
Filing date	Jun 18, 2013
Priority date	Jun 21, 2012
Publication date	Aug 7, 2018
Grant date	Aug 7, 2018

Abstract

A prosthesis comprising a tissue expander and one or more samples of graft material, wherein the tissue expander is attached to the one or more samples of graft material in a manner that allows the tissue expander and the one or more samples of graft material to be implanted in a patient as a unitary prosthesis; and wherein tissue expander is attached to the one or more samples of graft material in a manner that will allow the tissue expander and the graft material to separate after a period of time following implantation to allow removal of the tissue expander from an implant sites while leaving the graft material within the implant site, the prosthesis comprises a tissue expander having molded grooves, slots, channels, or other shallow cavity spaces on a surface, and wherein the graft material is within the grooves, slots, channels, or other shallow cavity spaces, securing the graft material to the tissue expander.

First claim

What is claimed is:

1. A prosthesis comprising:
a tissue expander comprising molded grooves, slots, or channels on a surface of the tissue expander; and
one or more samples of graft material comprising adipose tissue matrix releasably coupleable to the tissue expander in a manner that allows the tissue expander and the adipose tissue matrix to be implanted in a patient as a unitary prosthesis,
wherein the adipose tissue matrix further comprises shaped protrusions that conform to the inner surfaces of the grooves, slots, or channels on the surface of the tissue expander to releasably couple the adipose tissue matrix to the tissue expander, and
wherein the adipose tissue matrix is configured to release from the tissue expander as the tissue expander is enlarged after implantation.

2. The prosthesis of claim 1 , wherein the adipose tissue matrix comprises an acellular adipose tissue matrix.

3. The prosthesis of claim 2 , wherein the adipose acellular tissue matrix has been treated to produce a three-dimensional porous or sponge-like material.

4. The prosthesis of claim 1 , wherein the adipose tissue matrix is configured to release from the tissue expander as a frictional force holding the adipose tissue matrix in place lessens after implantation.

5. The prosthesis of claim 1 , wherein the adipose tissue matrix is configured to release from the molded slots, grooves, or channels as the tissue expander is filled after implantation, thereby stretching the edges of the molded slots, grooves, or channels and removing a frictional force coupling the adipose tissue matrix to the tissue expander.

6. The prosthesis of claim 1 , wherein the shaped protrusions are configured to release from the molded slots, grooves, or channels as the tissue expander or the adipose tissue matrix deforms following implantation thereby lessening a frictional force coupling the adipose tissue matrix to the tissue expander.

Assignees

• Lifecell Corp

Inventors

• Ansorge Heather
• Lapitan Lawrence
• Hayzlett Mark
• Kabaria Nimesh
• Hull Raymond
• Sun Wenquan
• Taenzer Michael
• Amato Matthew
• Roock Timothy
• Lee Dennis

Classifications

• A61F2230/0086

  Pyramidal, tetrahedral, or wedge-shaped · CPC title

• A61F2230/0093

  Umbrella-shaped, e.g. mushroom-shaped · CPC title

• A61F2220/0016

  with sharp anchoring protrusions, e.g. barbs, pins, spikes · CPC title

• A61F2250/0024

  made from both porous and non-porous parts, e.g. adjacent parts · CPC title

• A61F2220/0091

  connected by a hinged linkage mechanism, e.g. of the single-bar or multi-bar linkage type · CPC title