Urine sample analyzer, urine sample dispensing method and urine sample analyzing method

Patent metadata

Field	Value
Publication number	US-10024843-B2
Application number	US-201615079885-A
Country	US
Kind code	B2
Filing date	Mar 24, 2016
Priority date	Mar 31, 2015
Publication date	Jul 17, 2018
Grant date	Jul 17, 2018

Abstract

Disclosed is a urine sample dispensing method. The method comprises: (i) suctioning a urine sample using a nozzle; (ii) flowing the urine sample suctioned by the nozzle through a filter for capturing foreign matter, the filter being provided in a flow path connected to the nozzle; and (iii) changing a flow course of the urine sample or a position of the filter so that the filter is not positioned on the flow course of the urine sample, when the urine sample that has passed through the filter is discharged from the nozzle.

First claim

What is claimed is:

1. A urine sample analyzer comprising:
a nozzle which suctions and discharges a urine sample;
a pressure source which generates pressures to suction and discharge the urine sample;
a first flow path from the nozzle to the pressure source;
a second flow path which branches from the first flow path at a first position of the first flow path, and which conjoins with the first flow path at a second position on the pressure source side of the first position;
a filter for capturing foreign matter, which is placed in the first flow path between the first position and the second position;
valves which control a flow of fluid in a flow path circuit that includes the first flow path and the second flow path;
a controller which controls the valves so that the urine sample suctioned by the nozzle passes through the filter, and the urine sample that has passed through the filter bypasses the filter by passing through the second flow path and is discharged from the nozzle;
a detector which detects information of material components in the urine sample discharged by the nozzle; and
an analyzing part which analyzes the information of the material components detected by the detector.

2. The urine sample analyzer of claim 1 , wherein
the controller controls the valves to move all the suctioned urine sample from the second position to the pressure source side.

3. The urine sample analyzer of claim 2 , wherein
the controller controls the valves to continue a suction operation by the nozzle until all the urine sample is moved from the second position to the pressure source side.

4. The urine sample analyzer of claim 1 , wherein
the first flow path is filled with liquid at least between the first position and the second position, and the second flow path is filled with air, prior to suctioning the urine sample.

5. The urine sample analyzer of claim 1 , wherein
the controller controls the valves to flow liquid in a course through the second flow path to the nozzle to wash the second flow path after the urine sample has been discharged from the nozzle, and thereafter flows liquid in a course through the first position and the second position in the first flow path to the nozzle to wash between the first position and the second position of the first flow path.

6. The urine sample analyzer of claim 5 , wherein
the controller controls the valves to fill liquid between the first position and the second position in the first flow path and fill air in the second flow path after washing between the first position and the second position in the first flow path, and thereafter controls the valves to suction a next urine sample.

7. The urine sample analyzer of claim 1 further comprising:
a holding chamber for holding the urine sample that has been discharged from the nozzle;
a second nozzle for suctioning the urine sample from the holding chamber;
wherein the second nozzle has a smaller flow path diameter than the nozzle.

8. The urine sample analyzer of claim 7 further comprising:
a third flow path connected to the second nozzle;
wherein the third flow path is a filterless flow path which is not provided with a filter to capture foreign matter.

9. The urine sample analyzer of claim 1 , wherein
the pressure source is a syringe pump.

10. The urine sample analyzer of claim 1 , wherein
the nozzle is configured to suction the urine sample from a sample container;
the controller controls a discharge of the urine sample which has been suctioned from the sample container by the nozzle back to the sample container in order to mix the urine sample in the sample container.

11. The urine sample analyzer of claim 10 , wherein
the nozzle comprises a mixing nozzle which mixes the urine sample in the sample container, and a suction nozzle which suctions the urine sample from the sample container after the urine sample is mixed.

12. The urine sample analyzer of claim 11 further comprising:
a diaphragm pump for generating a pressure for mixing the urine sample in the sample container.

13. The urine sample analyzer of claim 1 , wherein the detector comprises:
a flow cell through which flows a measurement sample prepared from reagent and the urine sample suctioned by the nozzle;
a light irradiator for irradiating light on the measurement sample flowing through the flow cell;
a light receiver for receiving light given off from the material components in the measurement sample irradiated by light;
wherein the analyzing part analyzes characteristics parameters of the light received by the light receiver.

Assignees

• Sysmex Corp

Inventors

• Tsuji Kentaro
• Okamura Yuta
• Senda Go

Classifications

• B01L2300/0636

  Integrated biosensor, microarrays · CPC title

• G01N2035/106

  by sucking and blowing · CPC title

• A61B10/007

  for taking urine samples (measuring urological functions A61B5/20; genital receptacles A61F5/451; urinals for bed-ridden persons A61G9/006) · CPC title

• G01N35/1004

  Cleaning sample transfer devices · CPC title

• G01N33/493 Primary

  urine · CPC title