Biosensor chip, and biosensor device equipped with same

Patent metadata

Field	Value
Publication number	US-10023897-B2
Application number	US-201414501848-A
Country	US
Kind code	B2
Filing date	Sep 30, 2014
Priority date	May 16, 2012
Publication date	Jul 17, 2018
Grant date	Jul 17, 2018

Abstract

A biosensor chip is placed in a biosensor device and is rotated while a biochemical analysis specimen is measured, the biosensor chip comprising a main body, a holding chamber, a dispensing chamber, a plurality of quantification chambers, and a plurality of measurement chambers. The main body has an inlet into which the specimen is poured. The holding chamber holds the poured specimen inside the main body. The dispensing chamber is connected to the holding chamber via a first channel and dispenses the specimen. The quantification chambers are connected to the dispensing chamber, hold a specific amount of the dispensed specimen, and are disposed at positions located away from a rotational center of a rotary motion according to a distance from the first channel. The measurement chambers are connected to the quantification chambers via a second channel and react the specimen with a biochemical analysis reagent.

First claim

The invention claimed is:

1. A biosensor chip that is positioned in a biosensor device and is rotated while a biochemical analysis specimen is measured, the biosensor chip comprising:
a main body having an inlet into which the specimen is poured;
a holding chamber configured to hold the specimen which has been poured inside the main body;
a dispensing chamber connected to the holding chamber via a first channel, and configured to dispense the specimen;
a plurality of quantification chambers including (i) a first quantification chamber connected to the dispensing chamber, configured to hold a specific amount of the specimen which has been dispensed, and disposed at a second distance from a rotational center of a rotary motion and at a first distance from the first channel, and (ii) a second quantification chamber connected to the dispensing chamber and the first quantification chamber, configured to hold a specific amount of the specimen which has been dispensed, and disposed at a fourth distance which is larger than the second distance from the rotational center of the rotary motion and at a third distance which is larger than the first distance from the first channel; and
a plurality of measurement chambers each connected to the first quantification chamber and the second quantification chamber via a second channel, and configured to react the specimen with a biochemical analysis reagent, wherein:
the dispensing chamber is fan-shaped in plan view,
the fan-shaped dispensing chamber includes a first end and a second end at respective end portions on respective sides of the fan-shaped dispensing chamber,
the first end is disposed at a distance from the first channel, and the second end is disposed at a distance from the first channel that is larger than the distance from the first channel at which the first end is disposed,
the fan-shaped dispensing chamber is defined such that a radial length of the first end from the rotational center of the rotary motion is shorter than a radial length of the second end from the rotational center of the rotary motion, and
the quantification chambers are disposed radially outward from the dispensing chamber so that a distance from the center of the rotary motion increases in stages for each of the quantification chambers.

2. The biosensor chip according to claim 1 ,
further comprising an overflow chamber,
wherein the overflow chamber is disposed at a distance from the first channel that is larger than the third distance,
wherein the overflow chamber is configured to hold any specimen that overflows from the first quantification chamber and the second quantification chamber during the rotary motion.

3. The biosensor chip according to claim 2 ,
wherein the overflow chamber is disposed at a distance from the rotational center of the rotary motion that is larger than the fourth distance.

Assignees

• Panasonic Healthcare Co Ltd
• Phc Holdings Corp

Inventors

• Mori Kazuyoshi
• Kouge Masahiro
• Kitawaki Fumihisa
• Matsumura Takako
• Onishi Seiji

Classifications

• B01L2300/043

  Hinged closures · CPC title

• B01L2400/0677

  phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers · CPC title

• G01N33/487

  of liquid biological material · CPC title

• B01L2300/042

  Caps; Plugs · CPC title

• B01L2200/16

  Reagents, handling or storing thereof · CPC title