Microfluidic system
US-9314791-B2 · Apr 19, 2016 · US
US10022736B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10022736-B2 |
| Application number | US-201214232711-A |
| Country | US |
| Kind code | B2 |
| Filing date | Aug 23, 2012 |
| Priority date | Aug 26, 2011 |
| Publication date | Jul 17, 2018 |
| Grant date | Jul 17, 2018 |
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Described is a reusable fitting for attaching a conduit to a port. The fitting includes a housing, a spring, a retainer and a cap. The retainer is capable of locking and unlocking a conduit in the fitting. The fitting provides a high pressure fluid-tight seal and a substantially zero void volume at the junction of two fluidic conduits. The fitting is removable, reusable and replaceable, and allows a user to make and remake connections of a capillary to a fluidic port without permanently binding a ferrule to a specific capillary and thus to a specific port. The fitting can be replaced if part or all of the fitting is damaged during use.
Opening claim text (preview).
What is claimed is: 1. A reusable fitting for attaching a conduit to a port, comprising: a housing comprising a chamber and a ferrule portion at a proximal end of the housing; a spring disposed inside the chamber; a retainer disposed inside the chamber between a first end of the spring and the housing, the retainer formed as a single integral body and having a first opening for admitting a distal portion of a conduit and for admitting a retention feature fixed to a proximal end of the conduit to limit axial movement of the conduit in a distal direction, the retainer having an inner surface at a distal end of the retainer configured to engage the first end of the spring and having a slot at a proximal end of the retainer, a portion of the slot being aligned with the passage defined by the ferrule portion of the housing for receiving the conduit, the slot having a first inner surface that defines the first opening to receive the retention feature and a second inner surface that defines a second opening that is smaller than the first opening and sized to pass the conduit and impede the retention feature, the slot further including an off-center opening which is a radial extension in relation to the first and second inner surfaces; and a cap attached to a distal end of the housing and engaging a second end of the spring to urge the spring against the retainer to thereby urge the conduit in a proximal direction. 2. The fitting of claim 1 wherein the ferrule portion has a bore defining a passage for receiving a conduit. 3. The fitting of claim 2 wherein the chamber has a width greater than the bore of the ferrule portion. 4. The fitting of claim 1 wherein at least a portion of the chamber is internally threaded. 5. The fitting of claim 4 wherein a surface of the cap is threaded for engaging the internally threaded portion of the chamber to enable the cap to be tightened to the housing. 6. The fitting of claim 1 wherein the ferrule portion is formed of polyetheretherketone. 7. The fitting of claim 1 wherein the housing is formed of polymer or steel. 8. The fitting of claim 1 wherein an exterior surface of the housing is threaded for attachment to a port. 9. The fitting of claim 1 wherein the retention feature comprises a sleeve disposed on the proximal portion of the conduit. 10. The fitting of claim 9 wherein the sleeve is formed of steel. 11. A liquid-chromatography device, comprising: a conduit for communicating a fluid; a port in fluid communication with the conduit; and a fitting for attaching the conduit to the port, the fitting comprising: a housing comprising a chamber and a ferrule portion at a proximal end of the housing; a spring disposed inside the chamber; a retainer disposed inside the chamber between a first end of the spring and the housing, the retainer formed as a single integral body and having a first opening for admitting a distal portion of a conduit and for admitting a retention feature fixed to a proximal end of the conduit to limit axial movement of the conduit in a distal direction, the retainer having an inner surface at a distal end of the retainer configured to engage the first end of the spring and having a slot at a proximal end of the retainer, a portion of the slot being aligned with the passage defined by the ferrule portion of the housing for receiving the conduit, the slot having a first inner surface that defines the first opening to receive the retention feature and a second inner surface that defines a second opening that is smaller than the first opening and sized to pass the conduit and impede the retention feature, the slot further including an off-center opening which is a radial extension in relation to the first and second inner surfaces; and a cap attached to a distal end of the housing and engaging the second end of the spring to urge the spring against the retainer to thereby urge the conduit in a proximal direction. 12. The liquid-chromatography device of claim 11 wherein an exterior surface of the housing is threaded for attachment to the port. 13. The liquid-chromatography device of claim 11 wherein the ferrule portion is formed of polyetheretherketone. 14. The liquid-chromatography device of claim 11 wherein the housing is formed of polymer or steel. 15. The liquid-chromatography device of claim 11 wherein the retention feature comprises a sleeve disposed on the proximal portion of the conduit. 16. The liquid-chromatography device of claim 15 wherein the sleeve comprises steel. 17. A kit having component parts capable of being assembled to form a reusable fitting for attaching a conduit to a port, the reusable fitting comprising: a housing comprising a chamber and a ferrule portion at a proximal end of the housing; a spring disposed inside the chamber; a retainer disposed inside the chamber between a first end of the spring and the housing, the retainer formed as a single integral body and having a first opening for admitting a distal portion of a conduit and for admitting a retention feature fixed to a proximal end of the conduit to limit axial movement of the conduit in a distal direction, the retainer having an inner surface at a distal end of the retainer configured to engage the first end of the spring and having a slot at a proximal end of the retainer, a portion of the slot being aligned with the passage defined by the ferrule portion of the housing for receiving the conduit, the slot having a first inner surface that defines the first opening to receive the retention feature and a second inner surface that defines a second opening that is smaller than the first opening and sized to pass the conduit and impede the retention feature, the slot further including an off-center opening which is a radial extension in relation to the first and second inner surfaces; and a cap attached to a distal end of the housing and engaging the second end of the spring to urge the spring against the retainer to thereby urge the conduit in a proximal direction.
Joining by deforming · CPC title
relating to the construction of the column · CPC title
characterised by constructional or operational features · CPC title
placed in series · CPC title
end pieces · CPC title
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