Propellant-free aerosol formulation for inhalation
US-2015306087-A1 · Oct 29, 2015 · US
US10016568B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10016568-B2 |
| Application number | US-201213486522-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 1, 2012 |
| Priority date | Nov 25, 2009 |
| Publication date | Jul 10, 2018 |
| Grant date | Jul 10, 2018 |
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Official abstract text for this publication.
A nebulizer is proposed which includes an insertable container and a securing mechanism for holding the container in the nebulizer such that the container can move back and forth but can not be separated. The securing mechanism is formed by a metal unitary part. The securing mechanism forms a transportation lock for holding the container unmovable in the housing in a delivery state of the nebulizer. The securing mechanism forms a ring with flexible holding fingers.
Opening claim text (preview).
What is claimed is: 1. A container for holding a fluid, the container for insertion into a nebulizer, the container comprising: a base at a first end of the container; a neck at a second end of the container, the first and second ends of the container being at opposite extremes of the container; an at least essentially cylindrical housing portion extending from the base and toward the neck and terminating at an initial diameter of the container prior to the neck; a shoulder portion providing a transition in diameter from the initial diameter of the container where the cylindrical housing portion terminates to the neck portion; and an engagement mechanism operating to engage at least one holding element for holding the container inseparably in the nebulizer, the engagement mechanism being disposed on the cylindrical housing portion at an intermediate position between the base and the shoulder, wherein the engagement mechanism comprises at least two corrugations, each circumferentially extending about an entirety of the housing portion, and at least two corrugations being axially spaced from one another. 2. The container according to claim 1 , wherein the at least two corrugations are sized and shaped for engagement of, or cooperating with, the at least one holding element. 3. The container according to claim 2 , wherein the at least two corrugations each have an asymmetric profile in a direction of insertion in a longitudinal section of the container. 4. The container according to claim 2 , wherein the at least two corrugations each have a sawtooth profile with differently inclined ramp portions. 5. The container according to claim 2 , wherein: a vector extending from the base end toward the neck end defines both a longitudinal direction and a direction of insertion of the container into the nebulizer; the at least two corrugations each include a first portion that starts at the cylindrical housing portion and inclines away therefrom in a direction opposite to the longitudinal direction to an apex; and the at least two corrugations each include a second portion that starts at the apex of the first portion, and inclines toward and reaches the cylindrical housing portion in the direction opposite to the longitudinal direction. 6. The container according to claim 5 , wherein the first portion of the at least two corrugations has a first length, the second portion of the the at least two corrugations has a second length, and the first length is longer than the second length. 7. The container according to claim 5 , wherein: a first angle is formed between the first portion of the at least two corrugations and the cylindrical housing portion, a second angle is formed between the second portion of the at least two corrugations and the cylindrical housing portion, and the first angle is smaller than the second angle. 8. The container according to claim 7 , wherein: the first angle is between about 5 and 20 degrees; and the second angle is between about 40 and 90 degrees. 9. The container according to claim 5 , wherein a height from the cylindrical housing portion to the apex is at least one of: (i) at least 0.5 mm; (ii) at least 1.0 mm; and (iii) at least 2.0 mm. 10. The container according to claim 1 , wherein the engagement mechanism comprises a first inclined portion and a second portion inclined oppositely with respect to the first inclined portion. 11. The container according to claim 1 , wherein at least the housing portion is made of metal, and wherein the at least two corrugations are formed by deep-drawing or punch-drawing of the housing portion. 12. A container for holding a fluid, the container for insertion into a nebulizer, the container comprising: a base at a first end of the container; a neck at a second end of the container, the first and second ends of the container being at opposite extremes of the container; an at least essentially cylindrical housing portion extending from the base and toward the neck and terminating at an initial diameter of the container prior to the neck; a shoulder portion providing a transition in diameter from the initial diameter of the container where the cylindrical housing portion terminates to the neck portion; an engagement mechanism operating to engage at least one holding element for holding the container inseparably in the nebulizer, the engagement mechanism being disposed on the cylindrical housing portion at an intermediate position between the base and the shoulder, where: (i) the engagement mechanism comprises at least one corrugation for engagement of or cooperating with the at least one holding element, (ii) a vector extending from the base end toward the neck end defines both a longitudinal direction and a direction of insertion of the container into the nebulizer, (iii) the at least one corrugation includes a first portion that starts at the cylindrical housing portion and inclines away therefrom in a direction opposite to the longitudinal direction to an apex, and (iv) the at least one corrugation includes a second portion that starts at the apex of the first portion, and inclines toward and reaches the cylindrical housing portion in the direction opposite to the longitudinal direction; and a securing mechanism operating to hold the container in an a dispenser inseparably, where the securing mechanism includes one or more securing elements that are flexed or moved outwards by inserting the container into the dispenser and flex or move backwards to secure the container against separation from the dispenser, wherein the securing mechanism engages the at least one corrugation at the second portion of the at least one corrugation.
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