Nutritional composition for promoting gut microbiota balance and health

Patent metadata

Field	Value
Publication number	US-10015978-B2
Application number	US-201514887497-A
Country	US
Kind code	B2
Filing date	Oct 20, 2015
Priority date	Nov 12, 2009
Publication date	Jul 10, 2018
Grant date	Jul 10, 2018

Abstract

Nutritional compositions are provided that comprise a fructo-oligosaccharaide (FOS) in an amount of 35 to 44% by weight; a polysaccharide that is not a partially hydrolyzed guar gum such as, for example, an arabinogalactan in an amount of 50% to 38% by weight; and inulin in an amount of 12% to 24% by weight. The FOS and the polysaccharide may be present in a weight ratio of about 1:1. More specifically, the FOS and inulin may be present in a weight ratio of about 7:3. Also provided are methods of promoting gut micro biota balance and health. The methods include administering an effective amount of the nutritional composition to patients in need of same.

First claim

The invention is claimed as follows:

1. A nutritional composition for administration to an individual, the nutritional composition comprising:
soluble fibers comprising a fructo-oligosaccharide (FOS) in an amount of about 35 to about 44% by weight; acacia gum (AG) in an amount of about 38% to about 50% by weight; and inulin in an amount of 12 to 24% by weight;
the FOS and the AG are present in a weight ratio of 62:38 to 38:62; and the FOS and the inulin are present in a weight ratio of 82:18 to 58:42.

2. The nutritional composition of claim 1 , wherein the soluble fibers consist of the FOS, the AG and the inulin.

3. The nutritional composition of claim 1 , wherein the FOS and the AG are present in a weight ratio of about 55:45 to about 45:55.

4. The nutritional composition of claim 1 , wherein the FOS and the inulin are present in a weight ratio of about 76:24 to about 64:36.

5. The nutritional composition of claim 1 , wherein the FOS is present in an amount between 1.5-5.5 g/L, the AG is present in an amount of about 2.5-5.5 g/L and the inulin is present in an amount of about 0.5-2.5 g/L.

6. The nutritional composition of claim 5 , the soluble fiber further comprising up to 10 g/L of partially hydrolysed guar gum.

7. The nutritional composition of claim 1 , further comprising at least one insoluble fiber in an amount effective to enhance digestive function in the individual, wherein the at least one insoluble fiber is selected from the group consisting of a soy fiber, an outer pea fiber and combinations thereof.

8. The nutritional composition of claim 7 , wherein the soluble fiber and the insoluble fiber are present in a ratio between about 1.5:1 and about 1:1.5, and the FOS and the AG are present in a total amount of about 2.5-3.5 g/L, the inulin is present in an amount of about 1.25-1.75 g/L, and the soy fiber and the outer pea fiber are each present in an amount of about 3.25-4.25 g/L.

9. The nutritional composition of claim 8 , wherein the soluble fiber and the insoluble fiber are present in a ratio between about 1.25:1 and about 1:1.25.

10. The nutritional composition of claim 1 further comprising at least one ingredient selected from the group consisting of: antioxidants, fish oils, DHA, EPA, vitamins, minerals, phytonutrients, protein, fat, probiotics, and combinations thereof.

11. The nutritional composition of claim 1 further comprising insoluble pea fiber in an amount between 5 and 10 g/L.

12. The nutritional composition of claim 1 wherein the amount of the AG is 38% to 44% by weight.

13. The nutritional composition of claim 1 wherein the amount of the AG is 40% to 42% by weight.

14. The nutritional composition of claim 1 wherein the amount of the inulin is 15% to 21% by weight.

15. The nutritional composition of claim 1 wherein the amount of the FOS is 38% to 44% by weight.

16. The nutritional composition of claim 1 wherein the amount of the FOS is 40% to 42% by weight.

Assignees

• Nestec Sa

Inventors

• Roughead Zamzam (Fariba)
• Benyacoub Jalil
• Roessle Claudia
• Mager Jennifer Rae
• Swanson Julie Ann
• Greenberg Norman Alan
• Bolster Douglas Richard
• Garcia Rodenas Clara Lucia
• Rochat Florence

Classifications

• A61P5/00

  Drugs for disorders of the endocrine system · CPC title

• A61P37/06

  Immunosuppressants, e.g. drugs for graft rejection · CPC title

• A61P37/04

  Immunostimulants · CPC title

• A61P43/00

  Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00 · CPC title

• A61P25/28

  for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia · CPC title