Expandable implant and implant system

Patent metadata

Field	Value
Publication number	US-10010327-B2
Application number	US-201113325906-A
Country	US
Kind code	B2
Filing date	Dec 14, 2011
Priority date	Dec 16, 2010
Publication date	Jul 3, 2018
Grant date	Jul 3, 2018

Abstract

An embodiment of the invention includes an expandable implant to endovascularly embolize an anatomical void or malformation, such as an aneurysm. An embodiment is comprised of a chain or linked sequence of expandable polymer foam elements. Another embodiment includes an elongated length of expandable polymer foam coupled to a backbone. Another embodiment includes a system for endovascular delivery of an expandable implant (e.g., shape memory polymer) to embolize an aneurysm. The system may include a microcatheter, a lumen-reducing collar coupled to the distal tip of the microcatheter, a flexible pushing element detachably coupled to an expandable implant, and a flexible tubular sheath inside of which the compressed implant and pushing element are pre-loaded. Other embodiments are described herein.

First claim

What is claimed is:

1. A system comprising:
a metal wire backbone including primary and secondary states;
a jointless monolithic cured first shape memory polymer (SMP) expandable embolic open-cell foam, covering at least 50% of the length of the backbone, which includes primary and secondary states;
a second SMP including a programmed primary state and a processed second state;
a pushing element detachably coupled to the backbone; and
a flexible tubular sheath;
wherein (a) the pushing element, the backbone, and the first SMP are collectively preloaded inside the flexible tubular sheath, (b) the primary state for the backbone is at least one of a coil and a helix and forms a framing structure configured to be located within an aneurysm; (c) in response to thermal stimulus the second SMP changes from the processed second state to the programmed primary state, (d) the first SMP and the sheath are configured to simultaneously slide within a microcatheter, (e) the first SMP is included in a first layer and the second SMP is included in a second layer; (f) the second SMP adhesively sticks and chemically bonds to both a metal surface of the backbone and to the first SMP, (g) the second layer is directly between the backbone and the first layer, (h) the second SMP directly contacts both the metal surface and the first SMP; and (i) the first SMP completely surrounds the backbone within a plane that is orthogonal to the long axis of the backbone.

2. The system of claim 1 , wherein the first SMP in the secondary state is radially compressed.

3. The system of claim 1 wherein the first SMP includes a thermoset SMP.

4. The system of claim 3 wherein the second SMP includes an additional thermoset SMP.

5. The system of claim 1 wherein the second SMP chemically bonds to both the metal surface of the backbone and to the first SMP based on a member of the group consisting of Vander Waals forces, covalent forces, ionic forces, and polar forces.

6. A system comprising:
a metal wire backbone including primary and secondary states;
a jointless monolithic cured first shape memory polymer (SMP) expandable embolic open-cell foam, covering at least 50% of the length of the backbone, which includes primary and secondary states;
a second SMP including a programmed primary state and a processed second state;
a pushing element detachably coupled to the backbone; and
a flexible tubular sheath;
wherein (a) the pushing element, the backbone, and the first SMP are collectively preloaded inside the flexible tubular sheath, (b) the primary state for the backbone is at least one of a coil and a helix and forms a framing structure configured to be located within an aneurysm, (c) in response to thermal stimulus the second SMP changes from the processed second state to the programmed primary state, (d) the first SMP is included in a first layer and the second SMP is included in a second layer, (e) the second SMP is chemically bonded to both a metal surface of the backbone and to the first SMP, (f) the second layer is directly between the backbone and the first layer, and (g) the second SMP directly contacts both the metal surface and the first SMP.

7. The system of claim 6 wherein the first SMP in the secondary state is radially compressed.

8. The system of claim 7 wherein the first SMP includes a thermoset SMP.

9. The system of claim 8 wherein the second SMP includes an additional thermoset SMP.

10. The system of claim 8 wherein the pushing element is a wire.

Assignees

• Wilson Thomas S
• Small Iv Ward
• Benett William J
• Ortega Jason M
• Maitland Duncan J
• Hartman Jonathan
• L Livermore Nat Security Llc
• Texas A & M Univ Sys

Inventors

• Wilson Thomas S
• Small Iv Ward
• Benett William J
• Ortega Jason M
• Maitland Duncan J
• Hartman Jonathan

Classifications

• A61B17/12113 Primary

  within an aneurysm · CPC title

• A61B2017/00871

  polymeric · CPC title

• A61M25/0668

  splittable, tear apart · CPC title

• A61M2025/0042

  Microcatheters, cannula or the like having outside diameters around 1 mm or less · CPC title

• A61B17/12145

  having a pre-set deployed three-dimensional shape (methods of manufacturing A61B2017/00526) · CPC title