2,5-disubstituted 3-methyl pyrazines and 2,5,6-trisubstituted 3-methyl pyrazines as allosteric SHP2 inhibitors
US-12565476-B2 · Mar 3, 2026 · US
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Semko Christopher patents
Semko Christopher is listed as an inventor on 25 patents in our database. Major assignees and classification codes are summarized below.
| Metric | Value |
|---|---|
| Inventor | Semko Christopher |
| Total patents | 25 |
| First publication | Jul 11, 2019 |
| Latest publication | Mar 3, 2026 |
Notable patents
Publications ranked by popularity score, then publication date.
Ras inhibitors
US-2025361245-A1 · Nov 27, 2025 · US
Compounds, complexes, and methods for their preparation and of their use
US-2025269037-A1 · Aug 28, 2025 · US
Substituted pyrazolopyrazines, imidazopyrazines and [1,2,4]triazolopyrazines as allosteric SHP2 inhibitors
US-12365688-B2 · Jul 22, 2025 · US
Ras inhibitors
US-12252497-B2 · Mar 18, 2025 · US
Ras inhibitors
US-2025074923-A1 · Mar 6, 2025 · US
Ras inhibitors
US-2025051306-A1 · Feb 13, 2025 · US
Ras inhibitors
US-12202845-B2 · Jan 21, 2025 · US
Bicyclic compounds as allosteric shp2 inhibitors
US-2024199616-A1 · Jun 20, 2024 · US
2,5-disubstituted 3-methyl pyrazines and 2,5,6-trisubstituted 3-methyl pyrazines as allosteric shp2 inhibitors
US-2024116878-A1 · Apr 11, 2024 · US
Recent patents
Latest publications not already listed above.
Pyridine compounds as allosteric shp2 inhibitors
US-2024092795-A1 · Mar 21, 2024 · US
Ras inhibitors
US-2023303591-A1 · Sep 28, 2023 · US
Substituted pyrazolopyrazines, imidazopyrazines and [1,2,4]triazolopyrazines as allosteric SHP2 inhibitors
US-11739093-B2 · Aug 29, 2023 · US
Pyridine compounds as allosteric SHP2 inhibitors
US-11673896-B2 · Jun 13, 2023 · US
2,5-disubstituted 3-methyl pyrazines and 2,5,6-trisubstituted 3-methyl pyrazines as allosteric SHP2 inhibitors
US-11661401-B2 · May 30, 2023 · US
Covalent ras inhibitors and uses thereof
US-2023100838-A1 · Mar 30, 2023 · US
Rapamycin analogs as mtor inhibitors
US-2023093861-A1 · Mar 30, 2023 · US
Ras inhibitors
US-2022396589-A1 · Dec 15, 2022 · US
Ras inhibitors
US-2021130326-A1 · May 6, 2021 · US
2,5-disubstituted 3-methyl pyrazines and 2,5,6-trisubstituted 3-methyl pyrazines as allosteric shp2 inhibitors
US-2021101870-A1 · Apr 8, 2021 · US
Rapamycin analogs as mtor inhibitors
US-2021094975-A1 · Apr 1, 2021 · US
2,5-disubstituted 3-methyl pyrazines and 2,5,6-trisubstituted 3-methyl pyrazines as allosteric SHP2 inhibitors
US-10590090-B2 · Mar 17, 2020 · US
Pyridine compounds as allosteric shp2 inhibitors
US-2020017517-A1 · Jan 16, 2020 · US
Bicyclic compounds as allosteric shp2 inhibitors
US-2020017511-A1 · Jan 16, 2020 · US
2,5-disubstituted 3-methyl pyrazines and 2,5,6-trisubstituted 3-methyl pyrazines as allosteric shp2 inhibitors
US-2019210977-A1 · Jul 11, 2019 · US
Major assignees
Companies most often associated with this inventor's publications.
| Assignee | Patents |
|---|---|
| Revolution Medicines Inc | 25 |
Top CPC classifications
Most common classification codes across this inventor's patents.
| CPC | Patents |
|---|---|
| A61P35/00 | 24 |
| C07D519/00 | 18 |
| C07D487/04 | 12 |
| C07D401/14 | 11 |
| C07D471/04 | 11 |