Macrocyclic cftr modulators
US-2026098060-A1 · Apr 9, 2026 · US
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Brotschi Christine patents
Brotschi Christine is listed as an inventor on 32 patents in our database. Major assignees and classification codes are summarized below.
| Metric | Value |
|---|---|
| Inventor | Brotschi Christine |
| Total patents | 32 |
| First publication | Apr 7, 2015 |
| Latest publication | Apr 9, 2026 |
Notable patents
Publications ranked by popularity score, then publication date.
Pyridin-3-yl derivatives
US-12479820-B2 · Nov 25, 2025 · US
Combination of macrocyclic cftr modulators with cftr correctors and / or cftr potentiators
US-2025268979-A1 · Aug 28, 2025 · US
Alkoxy-substituted pyridinyl derivatives as LPA1 receptor antagonists and their use in the treatment of fibrosis
US-12344597-B2 · Jul 1, 2025 · US
Macrocycles as cftr modulators
US-2024208992-A1 · Jun 27, 2024 · US
Pyridin-3-yl derivatives
US-2022251068-A1 · Aug 11, 2022 · US
Alkoxy-substituted pyridinyl derivatives as lpa1 receptor antagonists and their use in the treatment of fibrosis
US-2021246116-A1 · Aug 12, 2021 · US
Benzimidazole-proline derivatives
US-11040966-B2 · Jun 22, 2021 · US
Benzimidazole-proline derivatives
US-2019263797-A1 · Aug 29, 2019 · US
Benzimidazole-proline derivatives
US-10329287-B2 · Jun 25, 2019 · US
Recent patents
Latest publications not already listed above.
Crystalline salt form of (S)-(2-(6 chloro-7-methyl-1H-benzo[d]imidazol-2-yl)-2-methylpyrrolidin-1-yl)(5-methoxy-2-(2H-1,2,3-triazol-2-yl)phenyl)methanone as orexin receptor antagonist
US-10023560-B2 · Jul 17, 2018 · US
Use of benzimidazole-proline derivatives
US-9914721-B2 · Mar 13, 2018 · US
Crystalline form of (S)-(2-(6-chloro-7-methyl-1H-benzo[D]imidazol-2-yl)-2-methylpyrrolidin-1-yl)(5-methoxy-2-(2H-1,2,3-triazol-2-yl)phenyl)methanone and its use as orexin receptor antagonists
US-9914720-B2 · Mar 13, 2018 · US
Crystalline salt form of (s)-(2-(6-chloro-7-methyl-1h-benzo[d]imidazol-2-yl)-2-methylpyrrolidin-1-yl)(5-methoxy-2-(2h-1,2,3-triazol-2-yl)phenyl)methanone as orexin receptor antagonist
US-2018002317-A1 · Jan 4, 2018 · US
Benzimidazole-proline derivatives
US-2017305897-A1 · Oct 26, 2017 · US
Crystalline salt form of (S)-(2-(6-chloro-7-methyl-1H-benzo[d]imidazol-2-yl)-2-methylpyrrolidin-1-yl)(5-methoxy-2-(2H-1,2,3-triazol-2-yl)phenyl)methanone as orexin receptor antagonist
US-9790208-B2 · Oct 17, 2017 · US
Benzimidazole-proline derivatives
US-9732075-B2 · Aug 15, 2017 · US
Use of benzimidazole-proline derivatives
US-2017001985-A1 · Jan 5, 2017 · US
Crystalline form of (s)-(2-(6-chloro-7-methyl-1h-benzo[d]imidazol-2-yl)-2-methylpyrrolidin-1 -yl)(5-methoxy-2-(2h-1,2,3-triazol-2-yl)phenyl)methanone and its use as orexin receptor antagonists
US-2016368901-A1 · Dec 22, 2016 · US
Crystalline salt form of (s)-(2-(6-chloro-7-methyl-1h-benzo[d]imidazol-2-yl)-2-methylpyrrolidin-1-yl)(5-methoxy-2-(2h-1,2,3-triazol-2-yl)phenyl)methanone as orexin receptor antagonist
US-2016355506-A1 · Dec 8, 2016 · US
Orexin receptor antagonists which are [ortho bi-(hetero-)aryl]-[2-(meta bi-(hetero-)aryl)-pyrrolidin-1-yl]-methanone derivatives
US-9493446-B2 · Nov 15, 2016 · US
Azetidine amide derivatives as orexin receptor antagonists
US-9403813-B2 · Aug 2, 2016 · US
Pyrazole and imidazole derivatives useful as orexin antagonists
US-9303023-B2 · Apr 5, 2016 · US
Azetidine amide derivatives as orexin receptor antagonists
US-2016024064-A1 · Jan 28, 2016 · US
Lactam derivatives useful as orexin receptor antagonists
US-9242970-B2 · Jan 26, 2016 · US
Proline sulfonamide derivatives as orexin receptor antagonists
US-9211279-B2 · Dec 15, 2015 · US
2-(1,2,3-triazol-2-yl)benzamide and 3-(1,2,3-triazol-2-YL)picolinamide derivatives as orexin receptor antagonists
US-9150566-B2 · Oct 6, 2015 · US
Orexin receptor antagonists which are [ortho bi-(hetero-)aryl]-[2-(meta bi-(hetero-)aryl)-pyrrolidin-1-yl]-methanone derivatives
US-2015252032-A1 · Sep 10, 2015 · US
Proline sulfonamide derivatives as orexin receptor antagonists
US-2015246021-A1 · Sep 3, 2015 · US
Benzimidazole-proline derivatives
US-2015166527-A1 · Jun 18, 2015 · US
Major assignees
Companies most often associated with this inventor's publications.
| Assignee | Patents |
|---|---|
| Actelion Pharmaceuticals Ltd | 18 |
| Idorsia Pharmaceuticals Ltd | 16 |
| Boss Christoph | 4 |
| Brotschi Christine | 4 |
| Williams Jodi T | 4 |
Top CPC classifications
Most common classification codes across this inventor's patents.
| CPC | Patents |
|---|---|
| A61P25/00 | 24 |
| A61P25/22 | 20 |
| A61P43/00 | 18 |
| A61P25/20 | 18 |
| C07D403/14 | 18 |